The England striker has been sidelined for just over two months following surgery on damaged ankle ligaments.
Defoe returned to training almost a month ahead of schedule and is available to face the Gunners, with boss Harry Redknapp saying: "It's great to have him back. He's a fantastic goalscorer and he's different to anybody else. He certainly would've had six or seven goals by this stage of the season."
Source: PA
Source: PA