Both players stepped back into action as Spurs Reserves convincingly beat Palace 5-0 at Stevenage Borough.
But neither are expected to make the trip to Wigan on Saturday, reported The Daily Mirror today.
Routledge, who joined from Palace during the summer, fractured a foot in the opening game of the campaign. The winger looked lively in his 45-minute stint as Spurs took control of the FA Premier Reserve League encounter in the first half. Gardner - returning from rupturing his thigh muscle at Aston Villa on September 17 - played in defence for an hour before being replaced by Leigh Mills.