Following an impressive start to his reign at White Hart Lane, ex-Southampton boss Pochettino saw Spurs beaten 3-0 at home to a rampant Liverpool.
It continues Liverpool's impressive run against Tottenham, with Brendan Rodgers' side dishing out 4-0 and 5-0 thrashings in the league last year.
In fact, Spurs only managed to take one point against last season's top four sides, with Manchester City and Chelsea also recording big wins at their expense.
But Pochettino, who oversaw victories over West Ham and QPR in his opening two league games, wants his players to take the positives from their latest defeat - with a tricky trip to Sunderland coming on Saturday.
"We need to learn and we need to improve," he said.
"We need to build a strong team, a confident team and a solid team
In the 90 minutes, 3-0 is impossible to put forward an excuse, but when you analyse the game we get a lot of situations to improve on.
"In the future this is a good game to learn from for us when we need to compete with a big team and we need to improve our game
The fans watch and see that we need to improve and the changes from the past two months.
"You always need time and you need passion
You also need results and I think we are heading in the right way."
The transfer window for Tottenham saw five new faces arrive in north London, with Federico Fazio and Benjamin Stambouli later additions following moves for Eric Dier and Swansea pair Ben Davies and Michel Vorm earlier in the summer.
The club missed out on high-profile target Danny Welbeck, who moved to rivals Arsenal, but Pochettino is happy with his squad and was prepared for the tighter purse strings when he took over.
"My ambition is to try to strive to be on top (of the league)," he said.
"This is the process and we need to provide our players and our supporters and believe always - this is our objective.
"I'm very happy with the squad
We know that last season Tottenham made a big investment in players and spent a lot of money, this season was always to believe in those players and add balance to the squad and show that we are a very good squad."
Source : PA
Source: PA