Hossam Ghaly and Jermain Defoe were both in Tottenham's the starting XI.
Martin Jol demoted both Aaron Lennon and Robbie Keane to substitute roles.
Two further changes from midweek witnessed Teemu Tainio and Young-Pyo Lee both start so Didier Zokora and Benoit Assou-Ekotto completed the line-up of outfield players on the bench.
It was a typically tough encounter at Craven Cottage with Steed Malbranque and Michael Brown involved in several committed tackles on each other.
Vincenzo Montella scored from the penalty spot for the home side four minutes before Pascal Chimbonda equalised.
Ghaly had a chance after good work from Dimitar Berbatov and Defoe. The pitch wasn't suitable for a game of high quality. As Spurs began to take a foothold in proceedings Tom Huddlestone saw a long range effort sail just wide.
Tainio limped out after 26 minutes so on came Zokora, Paul Robinson did well to deny from Heider Helguson's close range effort.
Fulham's physical approach entered the game the longer it went on, just before half time Malbranque was himself booked, then then it was Brian McBride's turn to have a close range effort turned away by Robinson.
The home side carried on the second half as they started the first, Helguson was shown a second yellow card for a foul on Huddlestone.
Lennon replaced Ghaly after an hour and seven minutes later Keane was on for Defoe.
Martin Jol: "Fulham used a certain style against us and that could have been a problem but we matched them and that was good.
"I felt from the first moment they were very physical and we did better in that respect."
"In a good sense it was very much the same as last season and they were entitled to do that. I think we stood up and did something about it.
"We brought on Aaron Lennon and had more width and he was dangerous a couple of times. Steed Malbranque was on the left and gave us width that side and we just hoped Robbie Keane could create something.
"I am disappointed we didn't create more. We had a couple of opportunities in the first half with Dimitar Berbatov and Hossam Ghaly, but they didn't shoot.
"I was happy with our defensive performance because it's not easy. Michael said it hit him here (patting his shoulder)."
"Going to Fulham and snatching a draw was not something to be particularly proud of but, on the other hand, we have lost on our last four visits there. We kept a good shape at times.
"In the home game against Newcastle we gave away a match we should have won and we went over to Fulham wanting to be a bit more rigid.
"I was not happy because we weren't at a high level all the time in all departments, but I was still satisfied that we got something out of the game after falling behind.
"We wanted to exploit the situation of playing against ten men following the sending off of Helguson, but they scored and it was a poor position for us to be in. We had seven minutes to do something about it and luckily enough that is what we did."
Paul Robinson: "We deserved a draw in the end. It was a difficult place to come and it has been Fulham's home form here that has seen them stay in the Premiership.
"It was good to make the saves, the last few weeks have gone quite well for me and it was nice to feel needed again.
"We lacked a cutting edge, but we never really looked in too much trouble apart from the two stops. I was pleased with my own performance while disappointed over the result but, given our previous record here, maybe a point wasn't too bad."
"I think the referee didn't send Michael off because I was behind it and going to save the shot. Daws wasn't to know that and it was a difficult one for the referee to call."
Michael Dawson: "I had to lean into it to get near the ball but my hands weren't out wide, they were by my side and I had no intention of sticking my arm out to try and handball it. I tried to get the block in and I was disappointed, but luckily for myself and the team we managed to get back into it.
"I was absolutely gutted when the referee pointed to the spot after all the work we'd done. It was a tough place to go but I felt we fought well. They had two big guys up front so it was physical and there were plenty of aerial challenges."
Source: TottenhamHotspur.com