Calum Davenport picked up a groin injury in the Carling Cup win against Milton Keynes Dons on Wednesday night.
The central defender who broke his nose at Villa Park a fortnight ago was replaced at half time and wasn't in the squad at Watford on Saturday.
Paul Stalteri was also missing from the Premiership encounter at the weekend, after his appearance at the National Hockey Stadium.
Young-Pyo Lee has been out of contention since returning from international duty.
Source: TottenhamHotspur.com